Duphaston is a hormonal drug that is prescribed for some types of infertility, it is able to interfere with the reproductive processes and generate activity. Duphaston is created as an analogue of the hormone progesterone, synthesized by artificial means, therefore, Duphaston intake is associated with attempts to begin conception. The optimal days for the concept is the day of ovulation and two days before it. Ovulation can be detected by measuring basal body temperature in the middle of the menstrual cycle.
What is part of the drug?
The drug contains didrogesteron, a synthetic steroid hormone with multidirectional activity. Didrogesterone is progesterone, which is very close to natural. It protects against the increased risk of endometrial hyperplasia and endometrial cancer through the action of estrogens, with a deficiency of progesterones. Does not cause the effect of androgenization or virilization, does not prevent ovulation and does not increase body temperature. Didrogesteron undergoes rapid metabolism in the liver, the main metabolite - dichidrodidgogesteron.
Quickly absorbed. The maximum concentration is reached within 30-150 minutes after taking the drug. From the body is excreted mainly in the urine.
The drug contains lactose and has a negligible effect on the ability to drive vehicles.
When to use duphaston?
Indications include progesterone deficiency:
- dysmenorrhea (painful periods);
- secondary amenorrhea;
- intermittent menstrual cycle;
- abnormal vaginal bleeding;
- premenstrual syndrome;
- habitual miscarriage;
- risk of miscarriage;
- the inability to conceive a child related to the malnutrition of the yellow body (luteal insufficiency).
Prescribed as a dehydraton with the delay of menstruation or their absence (amenorrhea). In addition, the drug is indicated for women in hormone replacement therapy in combination with estrogen.
Before starting to use the product in the treatment of abnormal uterine bleeding, it is necessary to conduct research in order to determine the cause of bleeding.
- hypersensitivity to any of the components;
- a diagnosis or suspected cancer;
- during breastfeeding;
- cardiovascular diseases;
- vaginal bleeding of unknown cause.
During use, the product may cause a relapse or exacerbation in the following cases:
- severe liver disease.
Duphaston for the treatment of menopause symptoms is used if these symptoms adversely affect a woman’s life. The decision to start using the product along with estrogen should be made by the doctor, after a thorough assessment of the benefits and risks associated with the use of the medication. Before you start taking, you must pass an examination to exclude contraindications. Frequency of admission and frequency is prescribed by your doctor. Prolonged use of HRT may increase the risk of developing certain types of cancer (breast cancer, after 3 years of treatment, ovarian cancer), arterial and venous blood clots, pulmonary embolism, coronary heart disease.
Sometimes: dizziness and drowsiness, especially within a few hours after use. As well as menstrual irregularities (heavy bleeding, uterine bleeding, amenorrhea, painful and irregular menstruation), chest pain or tenderness. Infrequently: vomiting, depressed mood, weight gain, allergic skin rash, abdominal pain.
It is not recommended to administer mechanical means during the period of taking the drug. And also not recommended to use duphaston before menstruation.
Mode of application
Duphaston is a tablet containing 10 mg of dydrogesterone. Dose and duration of administration depends on the severity of the disease. The dose should be optimized for use evenly throughout the day. Shelf life 5 years. Before starting treatment, you should consult with your doctor. Self-medication is not recommended.
Djufaston for a call monthly: reviews
Anna 36 years: “I have been accepting Duphaston for 1.5 years. At first there were irregular cycles, or not at all. After taking this medication, I have my period, so I continue to take it.
Katerina 25 years old: "I had problems with menstruation, they were not for 2-3 months, the doctor said that they were caused by a lack of ovulation, and that he would return to normal after 6 cycles of Djufaston. Thank you. That's how it happened."
Veronika 40 years: "Hello girls. I know these problems. I struggled with them for 7 years and nothing, until finally, after taking Duphaston, my periods did not go back to normal and there were no side effects."
Duphaston is a drug that has proven itself for the treatment of female disorders. But his appointment must be agreed with the attending physician, continue under the supervision of a specialist.