Pfcm (soluble fibrin monomer complex) increased

If an operation is to be performed, in vitro fertilization, or you are waiting for a birth before you, then you will need to pass the FFC analysis. He is appointed and those who have heart problems, thrombosis and suspicion of thrombophilia. What kind of research is this, what result is the norm, what to do if rfmk is elevated, what does the decrease in this indicator mean?

Why evaluate hemostasis?

Rfmk raised: what does it mean

In the list of laboratory tests there is not only a familiar "clinic" and biochemistry. Here you can see the mysterious abbreviation PPMK, which stands for "soluble fibrin monomer complex". If you briefly and simply explain the meaning of this concept, then under it mean pieces of blood clots. If it turns out that their blood is too much, it means that a person has formed large blood clots.

PCMC is an indicator that makes it possible to assess hemostasis by determining the amount of fibrin-monomeric complexes in the plasma. An analysis (it is also called a “coagulogram” or “hemostasiogram”) will show how blood coagulates, whether a predisposition to thrombus formation has formed and whether there is a danger of a blockage of a vessel with a blood clot.

How to take the analysis of RFMK?

If you were given a referral to the RFMK, then you should not be afraid of such a diagnosis. For a patient, this is a standard blood test. Its fence is made from the cubital vein. The blood sample for the test is blood serum. To get it, the blood taken from the patient is placed in a centrifuge.

For the result to be reliable, one should prepare for the analysis: one should not drink alcohol, food or drink anything 8 hours before the diagnosis. The only exception is water. It is also forbidden to take any medication. It is advisable not to worry. Do not do heavy physical work.

Two analysis options are used - basic and advanced. First is the first. It helps to determine exactly where there are deviations from normal values. If required, they will also conduct extended diagnostics in order to establish the number of such deviations.

How much fibrin should be in the blood?

The norm for an adult is a negative value, that is, ideally, fibrin in the blood should not exist at all. Positive is considered to be the result in which the formation of fibrin is visible in the plasma for two and a half minutes. Using special formulas for the calculation, the diagnostician will translate the time of particle formation into the PMMK numerical values.

Normal FPCM - 3.38 + 0.02 mg per 100 ml. The maximum allowed is 4 mg.

If soluble fibrin monomer complexes are elevated, this indicates that hemocoagulation (thickening of the blood) is too intense. The greater the deviation from the norm, the greater the risk of blood clots in the blood vessels.

Why does the PFMC level change?

Why does the PFMC level change

Fibrin monomer complexes are increased in the event that the blood coagulation system is activated. The higher this figure, the greater the likelihood of blood clots and intravascular coagulation.

FCMK may exceed the norm for such reasons:


  • thrombophilia;
  • thrombosis;
  • hypercoagulable syndrome;
  • DIC syndrome;
  • hemorrhagic vasculitis;
  • pulmonary embolism;
  • severe trauma;
  • burn;
  • pathology of the liver.

Physiological factors:

  • pregnancy;
  • heavy physical labor;
  • strong stress;
  • birthdays.

Other reasons:

  • heredity;
  • poor lifestyle;
  • medications that affect coagulation, out-of-correct doses, or without the permission of the doctor.

How to change the rules if a woman is pregnant?

Reduce or not reduce AFMC

FAMC is a compulsory study for women in the situation, as it will inform the doctor about possible deviations in hemostasis. During pregnancy, it is extremely important that the optimal ratio of all blood elements is maintained. Excessive fibrin may result in the appearance of blood clots, and its lack leads to bleeding.

Often, after passing such an analysis, future moms are told that rfmk is elevated. What does it mean? In pregnancy, in order to prevent massive blood loss during labor, the body increases blood clotting. Therefore, the growth of fibrin in this state is normal. Nevertheless, there are certain boundaries of the FOMC for pregnant women. They are:

  • first trimester - 5.5 ml 100 ml;
  • the second - 6.5mgna100ml;
  • the third - 7,5mgna100ml.

"Gold standard" - 5 mg / ml.

If a woman in rfmc position is elevated, what does such a deviation mean and what consequences can it cause? This is highly undesirable because it can lead to:

  • develop thrombosis;
  • violation of the functions of the placenta;
  • death of fruit carp out in the morning;
  • disruption of pregnancy;
  • delayed child development.

Deviations from the norm with a minus sign should also alert the doctors, because it can complicate childbirth - to provoke large blood losses.

The decrease in PCV develops on the background of taking medications that prevent blood clotting (Heparin). It is considered as a side effect and is manifested by a tendency to bleed.

how to restore the normal balance of blood elements?

How to restore the normal balance of blood cells

To reduce or not to reduce the AFMC (especially during pregnancy), only the doctor decides. Independently no measures in this direction should be taken.

If the future mother's fibrin is elevated, then doctors often use expectant tactics. In some women, it remains high all the time (reaches 8, 9, 11 mg per 100 ml), but this does not affect the child, pregnancy and the health of the woman.

Curantil and Heparin are most often prescribed to reduce FDMC and normalize blood circulation. Sometimes Clexan, Fraxiparin (injections) are prescribed.

The analysis of the PCM does not refer to the standard examination, which is prescribed for any treatment to the doctor. There must be special reasons for it. If the doctor has issued a referral for such a diagnosis, then do not try to give it up, because blood clots are a real threat to life.

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