Glucose is the main source of energy in cellular metabolism, as well as a supplier of carbohydrates for parenteral nutrition with easy digestibility. It helps to increase the energy potential of the body and stimulates its main functions. So, glucose dropper: what is it used for?
When is glucose solution administered for infusions?
As a rule, for infusion, that is, intravenous administration by means of a dropper, 5% glucose solution is used, packaged in sealed plastic bags of 400 ml or bottles. The solution consists of the active substance, glucose and water for injection.
When administered intravenously, glucose is metabolized by acids, breaking down into carbon dioxide and water, while releasing energy. Subsequent pharmacodynamics is determined by the nature of the agent used, which is diluted with glucose.
Dropper with glucose is indicated in the treatment of diseases such as:
- shock condition;
- increased bleeding;
- diarrhea and vomiting;
- critical reduction of plasma sugar levels during hypoglycemia;
- acute heart failure;
- a sharp drop in blood pressure, characteristic of the state of collapse;
- fluid accumulation in the lungs;
- liver disease;
- infectious diseases;
- dehydration and carbohydrate depletion when normal consumption of food and fluids is limited;
- as a carrier and diluent of other combined medications.
Contraindications and precautions
Glucose infusions are contraindicated for people with such pathologies:
- decompensated diabetes;
- glucose intolerance, for example, in the case of metabolism of stressful situations;
- with hyperosmolar coma;
- in case of hyperglycemia and hyperlactaemia.
Cautions to use:
- Large volumes of solution infusion should be carried out under special supervision by patients with water intoxication, heart failure, the presence of fluid in the lungs or edema of the kidneys.
- Because of the risk of hyperglycemia, the solution must be carefully administered to patients who have had ischemic stroke.
- For traumatic brain injury, the solution for infusion should be used during the first day, carefully controlling the concentration of glucose in the plasma.
- Glucose should not be dripped at the same time, after and immediately before blood transfusion into the same vein, which can cause hemolysis and nonspecific agglutination.
- Intravenous administration of glucose solutions to infants, especially premature or low birth weight babies, requires careful control over the duration of treatment, since this category of patients has a significant risk of hyper- or hypoglycemia.
The duration of the introduction of an intravenous glucose solution and its dosage is prescribed taking into account several factors, such as the patient's age, weight, general condition and clinical picture. This may require careful monitoring of blood glucose levels.
For the treatment of dehydration and carbohydrate depletion, the following dosage is recommended:
- For adults: 0.5 - 3 l / 24 h.
- For children, including newborns, the dosage is calculated per kilogram of child's weight:
- body weight up to 10 kg - 100 ml per kilogram of weight during the day;
- weight from 10 to 20 kg - 1 l / kg / 24 h;
- more than 20 kg - 1.5 l / kg / 24 h.
To avoid the development of hyperglycemia, the rate of solution administration is regulated depending on the clinical picture. Maximum infusion rate:
- for adults - from 5 mg per kilogram of weight per minute;
- for children, including babies - 10 - 18 mg / kg / min.
If glucose is used for transportation and dilution, the recommended dosage is in the range of 50 to 250 ml for a single dose of the drug.
How to apply?
Glucose is administered intravenously with a dropper. When using the solution to dilute and administer additional therapeutic agents, the infusion is carried out according to the instructions for use of these drugs. For infusion you need sterile equipment, which must be sealed to avoid access to the air system.
Plastic bags should not be used for series connection, which carries the risk of air remaining in the first one before the end of the solution coming from the next, as air embolism may result. Pressure on flexible plastic bags for intravenous infusion to increase its speed can also cause an air embolism if residual air from the container was not completely removed before the solution was injected.
Additional drugs can be injected into the solution both before and during the infusion. The solution containing the medicinal additive must be used immediately, since it cannot be stored.
Side effect name
The immune system
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Glucose droppers are often used during pregnancy for hydration and as a means of transporting other drugs. At the moment there is no evidence of adverse effects of funds on the baby when using a 5% solution during pregnancy, childbirth and breastfeeding.
In addition to the considered dosage form, glucose is also produced in the form of a powder, tablets of 0.5 g of the active substance, ampoules for injection with a concentration of 1%, 25%, 40% and a volume of 10, 20 and 50 ml.