Hypertension becomes a real disease of the century. A huge number of people taking medicine for high blood pressure. The most common among them are Enap or Enalapril. What is better - patients usually find it difficult to answer. How similar are these known drugs and what is the difference between them?
Enap or Enalapril - is there any difference?
"Enap" is a trademark, and "enalapril" is the name of the active substance of the drug. The action of both is based on the suppression of the hormone angiotensin, which causes ailments of the heart and blood vessels, provokes the spasms of the latter. When the drug is in our body, enalaprilat is formed as a result of hydrolysis of the active substance, which inhibits the action of enzymes. As a result, angiotensin stops its transformation.
Drugs are great effect on the vessels and the heart, reducing the pressure gradually. They:
- dilate blood vessels;
- do not change the rhythm of the contractions of the heart;
- they improve blood flow in the kidneys, as a result of which their work improves;
- patient age does not affect the effect of the drug.
In both cases there will be similar indications, since the base of drugs is the same active substance. It:
- exacerbation of angina pectoris;
- prevention of heart attack and arrhythmias;
- heart failure;
- lack of full function of the left ventricle;
- ischemic disease
Contraindications and side effects
Both drugs have some contraindications. However, taking medication without a prescription, be sure to pay attention to them:
- sensitivity to the components of the drug.
Among the most common side effects can be identified:
- angina pectoris;
- feeling nauseous;
- heart attack;
- general weakness, anxiety;
- chronic fatigue syndrome;
- feeling of dryness in the mouth;
- noise in ears.
In order not to aggravate your condition, you should consult a doctor before taking the medications and not exceed the indicated dosage.
Enalapril: instructions for use
Since Enap and Enalapril are identical in composition, be sure to ask about the dosage and price of drugs. Tablets are available in dosages from 2.5 to 40 mg. At elevated pressure, the dose for adults can be from 5 to 20 mg, in extreme cases, to 40 mg. In heart failure, the minimum dose is 2.5 mg. In the case of diuretic intake, it is not necessary to exceed the dosage of 5 mg. In case of kidney failure, it is necessary to fix the level of creatinine. If it exceeds 30 ml per minute, the volume of Enalapril can be increased to 5 mg. If the creatinine level is below 30 ml, it is necessary to take the drug in a volume of 2.5 mg. The doctor chooses the dosage for the children, depending on the indication and the body's response to the composition of the drug. 2.5 mg per day is prescribed to small patients whose weight varies from 20 to 50 kg. For children weighing more than 50 kg, a dosage of 5 mg is suitable. You should be especially careful with these drugs during pregnancy. In the first trimester, you must take them only under the supervision of a doctor. Since the second trimester and while feeding the baby, Enap and Enalapril are not prescribed. If you need medication during lactation, then you need constant monitoring of pressure in the mother and the functioning of the kidneys in the baby.
In drugs Enalapril and Enap analogs may differ in the additional composition of drugs. As a rule, these are compounds that enhance the action of the basic substance. The main analogs include:
- Berlipril and others.
Indications for use and the main substance of the analogues are the same, however, each patient chooses the most suitable drug for him depending on the effect of additional compounds and the manufacturer. Among the suppliers of analogues are Germany, Holland, Hungary, Russia, India, Poland. If Enapa or Enalapril was not available at the pharmacy, you can purchase any of the alternatives, but you should consult your doctor first.
Is there any difference?
And yet many patients are interested in: Enap and Enalapril - what is the difference between the two drugs? The only significant difference that can be called is the price. Enalapril is a domestic drug, and costs 3-4 times less than Enap foreign production. It is supplied by the Slovenian pharmaceutical company KRKA. There is no significant difference between medicines, since the active ingredient is the same. The effect of taking Enap and Enalapril is the same, but the cost is different. However, here lies the main difference. Russian companies produce Enalapril. Many of them were discovered quite recently, and the quality of the drugs they produce can be questioned. In this regard, there are many fakes of enalapril, the receipt of which is difficult to control on the market. There is a German Enalapril and its Indian counterpart, which often appears as Enapril. Between these two suppliers, it is worth choosing a German company: although the Indian drug is cheaper, its quality is lower. Unlike its fellow pharmacists, the Slovenian company has reliable protection against fakes and is popular for its quality. So if there is an opportunity to pay more, it is worth choosing Enap Slovenian production. Patients in their responses find it difficult to say which is better - Enap or enalapril? Both drugs perfectly reduce the pressure, and the decrease occurs gradually. In particularly difficult cases, drugs are suitable even for children, if you do not increase the dosage specified by the doctor.
Enap and Enalapril - effective drugs that are able to gently and effectively reduce pressure, normalize cardiac activity, prevent heart disease. It is necessary to carefully consider the quality of the selected drug and its manufacturer. From this depends largely on the effect of the drug on the body and minimizing side effects.