"combibien" or "milgamma" - which is better

Vitamins of group B are in many respects responsible for maintaining a person’s nervous activity in a normal state. There are a number of nervous disorders that respond positively to treatment with agents with this vitamin complex. They also include the drugs "Combibipen" and "Milgamma", and what is better to take, you will learn by reading the article.

Comparative characteristics of drugs "Kombilipen" and "Milgamma"

Comparative characteristics of drugs

All B vitamins are important regulators of carbohydrate, fat and protein metabolism. They act in total as metabolism boosters. For the treatment of neuropathic pain from this group, use vitamins B1 - thiamine, B6-pyridoxine, B12 - cobalamin. They are part of the studied drugs.

So, thiamin is especially important for carbohydrate metabolism of nerves, brain and muscles. With its shortage, avitaminosis develops, which can provoke neuritis with paralysis and heart failure. Thiamine daily allowance for adults is from 1.0 to 1.2 mg.

Pyridoxine is involved in metabolic processes and cell growth. The heart, brain and liver can perform their functions only when sufficient amounts of pyridoxine are obtained. It is also a building material for nerve endings, which are responsible for the transmission of impulses between nerve cells. Per day you need to consume at least 1.2-1.6 mg of vitamin B6.

Cobalamin is needed mainly in metabolic processes that are associated with cell division and growth. This is an important factor in the formation of new blood cells. The average daily need of an adult is about 3 μg of cobalamin.

And now we will make a comparison of drugs on the main indicators.

When to take?



Neuralgic lesion of the trigeminal facial nerve

The need for restorative effects on the body

Alcoholic, diabetic and other polyneuropathies

Neuritis and neuralgia

Inflammatory processes in the facial nerve

Various polyneuropathy

Lower back pain due to cervical-brachial and radicular syndrome, intercostal space neuralgia, spinal pathologies, for example, during compression fracture


Herpes infections

Paralysis of the motor facial muscles

Dosage Form

Solution for injection intramuscularly in 2 ml ampoules

2 ml ampoules with a solution for intramuscular injections

Coated tablets, 100 mg

How to use?

In severe forms of the disease - one ampoule per day for a week. Then the maintenance dose is one ampoule no more than 2-3 times within seven days.

The initial dosage to quickly relieve pain is one ampoule intramuscularly per day or one pill per day.

With mild symptoms, a maintenance dose is prescribed.

Maintaining dosage - once a day, three times a day or 14 tablets per day per month.

The duration of the course is prescribed by the doctor individually, but can not exceed two weeks. If necessary, the therapy is continued with oral preparations containing B vitamins.

The duration of therapy is determined by the doctor.

Contraindications and possible side effects

Heart and vascular insufficiency

Children under 16 years old

Hypersensitivity to the composition of the drug

Acute or Severe Heart Failure

Pregnancy and breastfeeding

Heart rhythm and conduction disorders

It has side effects such as

Intolerance or an allergic reaction to the composition of the drug

allergic reaction


the appearance of acne, mainly on the face



Main side effects

increased heart rate up to tachycardia

rash, itching, swelling

systemic reactions such as sweating, bradycardia, convulsions, dizziness and nausea

Interaction with other substances

It is not used in conjunction with levodopa, riboflavin, phenobarbital, benzylpenicillin and dextrose.

Thiamine is cleaved by sulphate solutions, and toxins suppress other vitamins after disintegration.

Thiamine loses its effectiveness under the action of substances with a pronounced redox property.

The effect of B1 is suppressed by the presence of mercury chloride, tannin acid, acetates, as well as riboflavins, ammonium iron citrate, penicillin, glucose.

Cobalamin is blocked by heavy metals.

Pyridoxine has anparkinsonic action and reduces the effect of levodopa.

The action of cobalamin is blocked by heavy metal salts.


In ampoules of 2 ml, 10 pcs. - 250 rubles

A solution in ampoules of 2 ml, 10 pcs. - 450 rubles

Tablets 100 mg, 30 pcs. - 600 rubles

Review of analogues:

  • Neurobex is a multivitamin preparation of combined action with ascorbic acid and B vitamins. Available for oral administration only.
  • "Neurubin" is an analogue of "Milgamma" in injections and tablets, film-coated, with a wide range of biological activity in relation to nervous disorders.

Reviews will help determine the choice

It is possible, to make a choice and determine which is better - "Milgamma" or "Combibien", will help our users:

  • Nina: "If we choose, then the budget option is better, because after examining all the indicators, I practically did not find the difference. In fact, Combilipen is an analogue of Milgamma, it is almost twice as expensive at injections."
  • Denis: “I am engaged in professional sports, I recover after injuries only with“ Milgamma. ”The preparation is excellent, it is fast on its feet, it is only necessary to strictly observe the dosage and the regimen of administration, all the more there is an option in tablets.”

So, dear readers, we have tried to find the most objective information on these drugs and hope that it will help you make a choice, but it is better to consult with your doctor. Be healthy!

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