Ceftriaxone is an antibiotic that blocks the production of a substance such as murein. Due to this, harmful microorganisms are destroyed and die. This drug differs from others in that it is available only in injections and has a parenteral route of administration.

Ceftriaxone: indications for use

Ceftriaxone: indications for use

Doctors prescribe ceftriaxone in order to get rid of pathogenic agents such as staphylococcus, streptococcus, as well as protea and E. coli.

But it is worth noting the fact that many of them are resistant to ceftriaxone, so before prescribing this medicine, the physician must necessarily conduct a kind of analysis - a sensitivity test. Otherwise, the treatment will be in vain and will not bring any results.

After the drug is injected into the muscle, after 2.5 hours, its maximum plasma concentration occurs, but if the composition is administered intravenously, this process is accelerated and begins after the end of the injection.

As for the withdrawal of the injection, then 50% of it is removed by the kidneys, and the rest is the liver.

The instructions for use of Ceftriaxone indicated that he is able to deal with such pathogenic conditions:

  • Various respiratory diseases. This includes bronchitis, pneumonia, and lung abscess.
  • Inflammatory processes and infections - salmonellosis, peritonitis, and also typhoid fever.
  • Postpartum and postoperative period (in order to prevent external bacteria from entering the body).
  • Infections of the genital and urinary tract.
  • Life-threatening diseases - Lyme disease, endocarditis, and sepsis.
  • The antibiotic is effective for treating the skin as a result of wounds and burns received by a person.


How to dilute cytriaxone with lidocaine?

Injections of the drug must be diluted with lidocaine. In order to inject the antibiotic intramuscularly, it is recommended to use 1% lidocaine solution. If you store this solution at home, it will last for 6 hours. If you put it in the fridge, it will be valid for a day, only before use it must be set so that it warms to room temperature.

If the doctor attributed 1 g of antibiotic, then you need to take 2 bottles of 1% lidocaine, as well as a tube of ceftriaxone, in which there is 1000 mg. When 0.5 g of the drug is attributed, then you need to mix 1 ampoule of lidocaine with 0.5 g of antibiotic. As for side effects, they are quite rare. The drug is contraindicated in case of individual intolerance, the presence of serious diseases of the kidneys and liver.

Ceftriaxone: drug analogues

Ceftriaxone: drug analogues

Currently, pharmaceutical companies produce many analogues of the drug. Among them are antibiotics in pills such as Rocephin, Biotraxon, Cefaxone, Megion, and others.

Ceftriaxone, analogs in injections of which are presented together with the solvent, include 1% lidocaine. These are antibiotics such as rotsifen and rosin. Their advantages are as follows:

  • Lidocaine, which is included in them, does not need to be diluted and dispensed, it just needs to be collected in a syringe.
  • No need to purchase solvents.

Such analogues have a significant drawback - they are expensive.

In conclusion, it should be added that the antibiotic ceftriaxone, like its analogues, is prescribed by doctors quite often. This drug is effective, it becomes easier after the first dose, but you should not prescribe it yourself, as it is a strong medicine that can cause an unpredictable reaction from the body.