For the treatment of skin lesions, it is often necessary to use ointments based on synthetic hormones or antibiotics - for example, Triderm. It copes well with diaper dermatitis in babies, and with deprived inguinal region, and with more simple neurodermatitis, eczema, psoriasis. A significant drawback is the cost of the drug, which is in the range of 500-600 rubles per 15 g, as well as the hormonal basis. Is it possible to find something cheaper and safer, but with the same performance?
"Triderm": instructions for use and a general description of the drug
The form of release of this drug - ointment and cream, while they are absolutely identical to each other in the spectrum of action and concentration of their active substances. The only difference is in the consistency due to the presence of excipients: the cream is presented in the form of a gel-like mass, as a result of which one can often find references to the shampoo or Triderm gel, which does not exist.
- The active ingredients of the drug - betamethasone diproionate, in the amount of 643 μg per 1 g of the product, as well as clotrimazole and gentamicin. In the ointment, vaseline was noticed as auxiliary components, in the cream - spirits and phosphoric acid.
- "Triderm" is an hormonal drug - the main active substance in its origin belongs to synthetic hormones that are quickly addictive, so the use of the drug implies a short course without its subsequent repetition. At the same time, a corticosteroid has many side effects, including dermatitis of hormonal origin. It is allowed to use "Triderm" only in case of urgent need, not for preventive purposes. And if possible, experts advise to find an analogue of non-hormonal nature.
According to the action spectrum, “Triderm” has the ability to relieve inflammation and irritation, relieve itching, and disinfect. It is used as an antifungal, antiallergic and antibacterial drug aimed at combating secondary infections. The combination of synthetic hormone and antibiotic allows in the indications for the remedy to include the following problems:
- Ringworm in the groin area, candidiasis
- Streptococcus, Staphylococcus, Escherichia coli (symptoms)
- Lishai (including chubby)
- Dermatosis with a complication of secondary infection
- Allergic and atopic dermatitis
- Diffuse atopic dermatitis
The use of "Triderma" can only be external, undesirable during pregnancy and in children under 2 years old. Upon reaching this age, the drug is applied under the supervision of a physician, due to the higher sensitivity of the child to the synthetic hormone, and more active absorption of the agent into the baby’s blood. Among the side effects when using children ointment or cream, not only growth and developmental delay, but also headaches caused by increased intracranial pressure, disturbances in the pituitary and adrenal glands were observed.
- In children, “Triderm” can be used for 7 days, after which the course is completed even in case of incomplete recovery.
- In adults, the drug is used for 4 weeks (maximum period), after which the course is also mandatory. If the improvement has not been recorded, it is necessary to undergo an examination to confirm the established diagnosis.
- Regardless of the specific skin disease, Triderm is spread over the affected area with a very thin layer, slightly rubbing it into the skin. It is important to capture 2-3 mm of healthy skin around the inflammation. The imposition of an occlusive dressing, which will enhance the absorption of active substances into the blood.
- Particular caution is recommended to observe when applying the drug to open wounds, since the antibiotic will be absorbed into the blood in greater concentration, as a result of which side effects from its use are possible.
- The frequency of use "Triderma" in adults - 2 times a day, after waking up and before bedtime.
- It is important to remember that the drug is not applied to the area around the eyes, and its cancellation should be gradual, through a decrease in the frequency of use.
- It is undesirable to use other antibiotics during the course of treatment with "Triderm", especially from the group of aminoglycosides, since this leads to the manifestation of an allergic reaction.
A considerable number of cautions and side effects leads to the need to consider analogues of this drug, preferably non-hormonal nature. Are there any? And what is the difference in their impact?
Non-hormonal analogues "Treederm"
Of the proven agents that have a spectrum of action similar to “Triderm”, only 2 drugs can be considered non-hormonal analogues.-
Antihistamine gel, which is a blocker of H1-group receptors. The active ingredient of the product is dietated maleate, which relieves itching, the appearance of allergies, reduces the degree of inflammation by reducing the capillary permeability. Prolonged use may produce a weak sedative effect.
- The maximum concentration in the blood is reached after 2 hours, metabolized in the liver after 6 hours, is completely eliminated. Bioavailable 70%.
- Among the indications for the use of "Fenistil" are any skin manifestations of allergic reactions, itching of any genesis. Also, the tool is allowed for the purpose of prevention against allergies, because it acts gently and has a prolonged effect.
- Among the side effects of the drug is observed drowsiness and a decrease in concentration, with an overdose, nausea, dehydration, weakness and headache. "Fenistil" can enhance the effects of sedative and hypnotic drugs, slow down psychomotor reactions.
- Not allowed to receive in the 1st trimester of pregnancy and in children up to a year, as well as in bronchial asthma, glaucoma.
Anti-inflammatory ointment used against atopic dermatitis. Based on pimerocrolimus, it is produced in aluminum tubes from 15 to 100 g. It can be used in children at the age of six months and older, while its prolonged use is allowed - 6-12 months. It is proved that during such a period it not only relieves the skin manifestations of an allergic reaction, but also affects the frequency of exacerbations.
- The safety of the use of "Elidel" in immunocompromised individuals with severe skin lesions has not been studied. It is undesirable to use for external manifestations of malignant tumors, as well as for bacterial or fungal diseases.
- Among the side effects observed only increased blood flow to the place treated with ointment, as well as a slight burning or itching. Perhaps peeling of the skin, swelling. Symptoms go away independently, after drug withdrawal.
Analogs ointment "Triderm" Russian production
The remaining existing analogues of Triderma - cheap and not so much - are hormonal, mostly based on the same glucocorticoid. The main difference is observed in the price category of the drugs discussed below, as well as auxiliary components: antibiotics do not play their role everywhere.
Means based on betamethasone and salicylic acid, focused on dermatitis of various origins, psoriasis, lichen planus, ichthyosis and keratosis, dry skin and lupus erythematosus. The ointment has not only antipruritic and anti-inflammatory effects, but also keratolytic and antihistimine. Available in tubes of 20-40 g.
- The duration of the course of use of the ointment may exceed 28 days, but its use in this case should not be daily. If there is no effect of the drug on the skin after 4 weeks, the ointment should be replaced with another agent.
- If Belosalik is used for the treatment of chronic skin diseases, the use of the ointment is prolonged for 3-5 days in order to avoid relapse after the elimination of symptoms. During the year, repeated repetition of the procedure is allowed.
Akriderm GK and SK
It is a full-fledged Russian analogue of "Triderma", significantly winning in its price: a 15-gram tube costs 80 rubles. Moreover, they have exactly the same active ingredients - gentamicin and betamethasone for "Akriderm GENTA"; betamethasone, gentamicin and clotrimazole - for "Akriderm GK". There is also an option "Akriderm SK", based on betamethasone and salicylic acid. Depending on the composition, the range of action of the ointment and cream is determined.
- "Akriderm GK“as the most accurate analogue of Triderma, has exactly the same indications: an antifungal drug with an antibiotic and glucocorticoid works on pityriasis, ringworm, neurodermatitis, dermatosis.
- "Akriderm Sc"similar to Belosalik", being focused on dermatosis, ichthyosis, lichen planus, neurodermatitis.
- "Akriderm GENTA"affects dermatitis (including secondary), eczema, lichen, psoriasis, pruritus and diaper rash.
The duration of the course of any of the subspecies "Akriderma" should not exceed 4 weeks, while using with a frequency of 1-2 times per day, locally on the affected area. If hypersensitivity or other side effects are noted, the course is stopped.
The same Russian analogue "Triderma", but based on betamethasone and salicylic acid. It has anti-inflammatory and antipruritic action, removes the manifestations of an allergic reaction, softens the skin.
- The drug is indicated for psoriasis, eczema, coarsening and peeling dermatitis, neurodermatitis, ichthyosis, urticaria, lichen planus, exudative eczema, skin dyshidrosis.
- In children can be used from 2 years old, is not allowed during pregnancy and lactation, as well as in liver failure. It is undesirable in the process of applying an ointment to apply an occlusive dressing. Frequency of use - up to 2 times a day, in a thin layer, for 14-28 days.
It is unacceptable to use any of these ointments for herpes, chicken pox, syphilis, open wounds, cutaneous tuberculosis, pregnancy, lactation, and children under one year of age. Due to the activity of the central components, it is advisable to consult a doctor before using each drug.